The present research demonstrates a negative association
between the level of fat accumulation and the
Journal of Dairy Science Vol. 98 No. 7, 2015
insulin response of the glucose metabolism in pregnant
dairy cows at the end of the dry period. This impaired
insulin action at the level of the glucose metabolism
is characterized by both decreased insulin sensitivity
as well as decreased insulin responsiveness. Insulin
response of the FA metabolism, on the other hand,
was not associated with the level of fat accumulation.
Distinction between the insulin response of the glucose
and the FA metabolism was also obvious for the insulin
concentration needed to elicit half maximal effect. For
FA metabolism, the half maximal effect was reached at
lower insulin concentrations compared with the glucose
metabolism.