The purposes of this articlewere to investigate the influences of synthetic strategy on the CuO crystals using cellulose
as substrate. Exploring the influences of different synthesis methods is of great importance for the understanding
of the growthmechanism of CuO crystals. In this article, the productswere characterized by means of Xray
diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FT-IR),
scanning electron microscopy (SEM), thermogravimetric analysis (TGA), differential thermal analysis (DTA), and
cell cytotoxicity. Experimental results demonstrated the obvious differences in the CuO crystals between
microwave-assisted hydrothermal and hydrothermal methods in the existence of cellulose. These researches
do a favor for the understanding of growth mechanism of CuO crystals with different synthesis methods.