because fast and complete repair of the injured muscle is the obvious target, especially in athletes, attempts should be made to find clinically feasible modalities to enhance the proliferation phase of muscle regeneration.
cell transplantation has been used to overcome the loss of cells induced by lesions in many organs such as liver, heart and skeletal muscle. furthermore, in skeletal muscle injuries, a variety of cell types have been tested: myoblasts, which is the most used cell type, muscle-derived stem cells, hematopoietic stem cells, bone marrow-derived human mesenchymal cells, adipose-derived stem cells and BMMC.
BMMC have been reported to differentiate in vitro into contractile myotubes or convert into myogenic linage in vivo in response to physiological stimuli.