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As results of this investigation, the mean values for lead and cadmium in domestic and imported rice samples were considerably higher than the allowable limits set by FAO/WHO. The estimated weekly intake for lead in some brands of imported rice was considerably above than provisional tolerable weekly intake. The event was not observed in the domestic rice. According to the results of this study approximately 65.9% of the daily intake of cadmium comes from rice. Health risk will increase with consumption of other contaminated food that was not evaluated in this study. So, measurement of heavy metals in the complete diet over a specified period is recommended. According to the reports of the Institute of Standards and Industrial Research of Iran, rice is a dominating staple food in the diet of Iranian population. In the Shiraz, rice is the main food eaten one or two times a day. Thus, it is necessary that certified agencies monitor and evaluate the heavy metal levels in domestic and imported rice regularly.