Furthermore, assessment of the severity of the
NLFs was performed according to the WSRS scoring
system (1 = absent, 2 = mild, 3 = moderate,
4 = severe, and 5 = extreme).23 Before treatment
(baseline), the mean WSRS score of NLFs rated by
the evaluating investigator was 3.55 0.5 for the
patients treated with the PCL-based filler and
3.53 0.5 NASHA-based dermal filler. All post-treatment
time points show improvements in mean WSRS
scores (Fig. 1). Interestingly, significantly higher
improvements in mean WSRS scores were found for
the NLFs treated with the PCL-based filler compared
to the NLFs treated with the NASHA-based filler at 6