or fibrillation during electrophysiologic
studies and a recent episode of sustained VT or VF
were randomly assigned to receive fish oil, 1.8 g/day, 72% ω-3 fatty
acids, or placebo and were followed up for a median of 718 days
(range, 20–828 days). According to Kaplan-Meier estimates, 28%
of patients in the fish oil group reached the primary endpoint of
VT, VF, or death compared to 39% of patients in the olive oil control
group. At the end of 12 months, the ω-3 fatty acid group
showed a trend toward a longer time to first ICD event (VT or VF)
or death, with a risk reduction of 28% (p = 0.057) that disappeared
at 6, 12, and 24 months observations. Recurrent VT/VF events
were more common in patients randomised to receive fish oil
(p