A novel integrative Fenton-like and upward flow biological filter bed (IBFB) has been constructed in this paper. In this IBFB, AO7 is almost completely degraded in the efficient Fenton-like pretreatment based on the active home-made catalysts. Moreover, the IBFB not only removes the detrimental effect of H2O2, but also turns it into DO. Thus, the IBFB attains higher COD removal than the traditional separate reactor. Another advantage is that the IBFB saves the regulation pool and the following pump. The novel IBFB offers a new idea to develop a high efficient Fenton-like and BFB joint process