The important chaperone function of Hsp90 is hijacked during cancer, so that mutated and overexpressed proteins are protected from misfolding and degradation. This promotes cancer survival in its stressful environment and promotes the ability of cancer cells to tolerate the many genetic alterations associated with cancer. - See more at: http://www.onclive.com/publications/Oncology-live/2012/April-2012/Targeting-Hsp90-Researchers-Aim-to-Thwart-Chaperones-of-the-Guardian-of-the-Proteome#sthash.i1iwnrmB.dpuf