The same diets that were used in the present study increased
the immune parameters of gilthead sea bream (S. aurata L.),
although this did not correlate with disease resistance to P. damselae
[25]. The present results demonstrate that the combination of
B. subtilis and inulin exerts a negative effect on gilthead sea bream
gut homeostasis (causing alterations in both gut morphology and
microbiota) which could explain, at least in part, the previous results.
More morphofunctional studies are needed in order to correlate
the nutritional and immune aspects of fish gut.