0:00
dementia is a chronic state of confusion in which the patient finds it hard to
0:05
remember
0:05
learn and communicate it is also characterized by the formation
0:11
of senile plaque involving the accumulation of beta-amyloid
0:15
and abnormal neural fibrillary tangles beta ameloid is derived from a larger
0:21
molecule called
0:22
amyloid precursor protein or appt
0:26
appt is normally present on the cell surface is
0:30
and the cleavage App results in the formation
0:33
a beta ameloid new role fibrillary tangles consist of
0:38
insoluble twisted fibers that are found
0:41
inside the brain cells the towel protein is abnormal
0:45
and the microtubule structures collapse
0:50
recent drugs like inhibitors up cerebral acetylcholine esterase
0:54
have been shown to be up some benefit to Alzheimer's patients