Participants in the theoretically-guided nurse case management with incentives and tracking (NCMIT) program received the following: (a) targeted hepatitis education session, conducted by a trained research nurse during the first session, incorporating information about HAV, HBV, HCV, and HIV infection; diagnosis; prevention; and transmission and about HAV/HBV vaccination, its administration schedule, possible side effects, and the importance of adherence to the vaccine series; (b) nurse case management, also conducted by a trained nurse, and incorporated seven sessions which included enhancement of personal (self-esteem), social, and behavioral coping skills; training in self-management and communications skill competencies necessary for overcoming barriers to completion of the HBV vaccination series; and skill competencies to reducing risky substance use and sexual practices, all sessions were preceded by a needs assessment and included referrals and appointments as needed; (c) client tracking by outreach workers; (d) incentives for receiving each dose of the vaccine ($5); and (e) a local community resource guide.