The experiment explored the impacts of polycyclic aromatic hydrocarbons (PAHs) and the prevalence of Aspidogastrea africanus (endoparasite) in Chrysichthys nigrodigitatus (host) in Lekki lagoon, Lagos State, Nigeria. Host-parasite allotment of PAHs, histopathological analysis, and the oxidative status of parasite and host were investigated.