Lumbar puncture
The AAP guidelines strongly recommend a lumbar puncture in any child who presents with a seizure, a fever and has meningeal signs and symptoms. It is also recommended in any child whose history or examination suggests the presence of meningitis or intracranial infection [45]. As part of the FEBSTAT study, cerebrospinal fluid (CSF) samples were reviewed for the 136 of the 199 children who had a nontraumatic lumbar puncture performed. The study confirmed that FSE rarely causes CSF pleocytosis [52]. The CSF glucose and protein levels of the sample were unremarkable, and the temperature, age, seizure focality, and seizure duration did not affect results. This supports that CSF pleocytosis should not be attributed to FSE