If HbA1c target not achieved after ~3 months of monotherapy, proceed to 2-drug combination (order not meant to donate any specific preference – choice dependent on a variety of patient- and disease-specific factor) :
If HbA1c target not achieved after ~3 months of dual therapy, proceed to 3-drug combination (order not meant to donate any specific preference – choice dependent on a variety of patient- and disease- specific factors):