a/AFE is sometimes preceded by prodromal symptoms such as fetal bradycardia (late decelerations) and/or meconium-stained amniotic fluid (fetal distress) followed by mother’s symptoms of AFE [17,24,28-33]. This is probably the earliest effect of amniotic fluid invasion into the utero-placental circulation (induction of local DIC and impaired oxygen supply to the fetus);