Current irritability was assessed based on patient recall of the number of days among the 10 days prior to enroll-ment during which they experienced any irritability on the STEP-BD Aective Disorders Evaluation. For the primary analysis, we examined current irritability dichot-omized according to the presence or absence of any irri-tability. For secondary analyses, we examined current irritability dichotomized according to the presence or absence of irritability for at least four and at least seven of the prior 10 days.