Tentative evidence suggests that QoL improves somewhat over the course of treatment.23,38,39 Diefenbach and colleagues37 investigated an OCD sample undergoing cognitive-behavioral therapy. They found symptom-correlated changes in QoL on social and family functioning. However, some increase in QoL seems to be independent of symp¬tom improvement.38 For example, Tenney and col¬leagues39 found that responders and non-responders showed equal improvement in QoL which was inter¬preted as a “non-specific treatment effect.” Likewise, our study10 found improved QoL in all patients. Increments in QoL at discharge could not be reliably predicted by baseline characteristics. Responders exceeded non-responders only on the SF-36 vitality subscale. Another study40 reported a decline of QoL at the follow-up period, despite continued symptom improvement, further suggesting that QoL is not directly tied to OCD symptom severity. Recently,41 subsamples with heterogeneous outcome patterns were described as follows: a group exhibiting strong symptom reduction accompanied with very good QoL gains, a second group with significant symp¬tom reduction but less robust QoL improvements, and a third group with limited symptom gains and even decrements in QoL.