The evaluation of cell viability by MTT test on human fibroblasts and keratinocytes after application of SLN and SLN containing prednicarbate showed a viability >90%.
Cell viability evaluated by MTT test after application of prednicarbate containing SLN to reconstructed epidermis was 94.5% (Santos Maia et al., 2000).
This shows a good tolerability of the carrier system by the skin.