30. Cholera vaccines
• Parenteral cholera vaccine not recommended by WHO (low protective efficacy and adverse reaction)
• Two types of safe and effective oral cholera vaccines currently available
Both are whole-cell killed vaccines
Both have sustained protection of over 50% lasting for two years in endemic settings.
Both vaccines are WHO-prequalified and licensed over 60 countries.
Both vaccines are administered in two doses given between seven days and six weeks apart