The purpose of this study is a development of database system for clinical management in patients with coronary artery disease. The pairwise t-test was done to compare the before and after intervention effect for the health promotion practice of cardiac patients by the information application. The present research showed that practice rate of health promotion application. The present research showed that practice rate of health promotion using database system in an effort to reduce inefficiency and improve reliability of information. By the adoption of this database system, the medical information. By the adoption of this database system, the medical information can be effectively connected with other databse sytem. preated in urban area from September 1, 2011 to December 31, 2011. The pairwise ttest was done to compare the drug misuse and abuse before and after computer-aided education. The present research showed that drug misuse and abuse decreased to 54.9-67.1% by the computer-aided education. This paper resulted in significant positive effects in quality of life of patients with drug misuse and abuse and its implications could be used as the basic data for developing further systematic materials on computer-aided education.