Sustainable agriculture must provide for growing human demands for crops while minimizing impacts
on ecosystems. This is a daunting challenge as agroecosystems have trended towards monocultures with
intensive synthetic inputs. Moreover, agricultural landscapes often lack natural habitats that are necessary
to support biodiversity. Furthermore, problems associated with agricultural intensification and
land-use change may be exacerbated by climate change, which increases the frequency of disturbances,
modifies the suitability of habitats, and changes the way species interact. To meet this challenge, farmers
must increasingly rely on integrated pest management strategies, including biological control. Biological
control of arthropods, weeds, and diseases can promote the stability and diversity of agricultural communities
and aid in reducing synthetic inputs. Promoting biological control may thus help farming systems
adapt to a rapidly changing world. This special issue considers how multiple global change drivers such
as agricultural intensification, land-use change, and climate change affect biological control. Here, we discuss
these papers and highlight concepts that remain relatively unexplored in the context of global
change and biological control. Future research addressing these issues will promote biological control
and enhance agricultural sustainability in a rapidly changing world.