The adequate provision of basic infrastructure and financial resources will play a vital role in the adoption of open source biotechnology. Education forms the basis through which open source development can be promoted among the citizens, therefore quality education on ICT programs should be provided to encourage wide participation from the grass-root levels. The lack of political support due to a low level of awareness among the government officials on open source in developing countries can slow down open source development. Therefore, a concerted effort should be made to educate and encourage government officials in all relevant institutions. Given the impact of IPRs in creating a research environment for biotechnology, the IPRs system must be designed in a research-friendly way, particularly with regards to protection under law that will facilitate commercialization and technology transfer to developing countries. Added to this, institutional and legal frameworks must be established and encouraged to protect IPRs in developing countries so as to enhance the economic benefit of open source biotechnology products.