On the basis of our previous results showing that OPS
modulated the T cell immunobalance toward the Th1-
dominant direction in OVA-primed splenocytes, and promoted Th1-type immunity in OVA-sensitized mice [7], we
hypothesized that OPS might be effective in modulating food
allergy, a predominantly Th2-type immune disorder. We
report here that oral administration with OPS attenuates intestinal allergic inflammation associated with food allergy.