However, the delivery efficiency of these materials plays a dominant role in
determining signal intensity. By identifying how size, shape, and chemistry influence the delivery
process, one is then able to redesign the nanoparticles so that they accumulate maximally in the
tumor. The fundamental studies on nano-bio interactions will enable the parameterization of
the nanoengineering process by creating specific design rules. This would enable researchers to
streamline the construction of complex nanostructures that ensure the highest possible delivery
efficiency while maximizing signal strength