1. Background
Dengue ranks as one of the most important mosquito-borne
viral disease in the world (WHO, 2012). The four serotypes of
dengue virus can cause a variety of clinical illnesses ranging from
mildly symptomaticdengue fever tomoredangerous clinical conditions
with capillary leakage syndrome, such as dengue hemorrhagic
fever and dengue shock syndrome (Gubler, 2004; Chaves et al.,
2014). Currently, dengue represents a large and growing public