Abstract
Behcet's disease (BD) is known for many year, yet its etiology remains unknown. In BD,the increased production of reactive oxygen species from activated neutrophils
may reduce concentrations of antioxidant vitamins and enzymes in plasma and red blood cells (RBC). Vitamin E is an important fat soluble antioxidant vitamins and Vitamin E role on antioxidant parameters of BD is unclear. The study was undertaken to evaluate the role of vitamin E on lipid peroxidation (MDA) levels, antioxidant vitamin and enzyme concentration in plasma and RBC in patients with BD, There were three groups i.e., control, patient and treatment group with twenty-five subjects in each Nonsmoking patients with BD, patient group, was compared with an equal number of healthy control subject (control group). Blood samples were taken from both control and patient groups and then oral vitamin E was daily supplemented to the patients with BD for six weeks (treated group). At the end of six weeks, blood was taken from the treated group once more.