There are several factors that may induce ulcer in human beings, such as stress, chronic use of anti-inflammatory drugs and continuous alcohol ingestion, among others. Although in most cases the etiology of ulcer is unknown, it is generally accepted that it is the result of an imbalance between aggressive factors and maintenance of the mucosal integrity through the endogenous defense mechanism. The candidate for an effective drug against peptic ulcer should basically act either by reducing the aggressive factors on gastroduodenal mucosa or by increasing mucosal resistance against them. A thorough literature review on Michelia champaca Linn showed that it was not tried out for any anti-ulcer effect. The phytochemical screening of Michelia champacaLinn showed the presence of flavonoids, tannins and proteins in the leaves(alcoholic and aqueous) and flower (alcoholic and aqueous) extracts. Leaf alcoholic extract showed the presence of alkaloids, glycosides, and sterols. The presence of carbohydrate was observed in the leaf alcoholic extract as well as flower aqueous and alcoholic extracts. The presence of flavonoids was ascribed to the Michelia species and it is well known that many flavonoids display anti- secretory and cytoprotective properties in different experimental models of gastric ulcer. In addition, oxidative damage is considered to be a common factor in the pathogenesis of ulcers by