there is a lack of a uniform definition of MOF. The use of
different scores of MOF hampers interpretation of the results of the
meta-analyses and therefore no firm conclusions can be drawn.
Additional studies are required to confirm the results of this study.
CONCLUSION
Identifying patients at high risk for MOF may guide the need for
monitoring of organ failure and may provide avoidance of therapy
, which can aggravate organ failure. Early hypocoagulopathy
and shock are risk factors for TIC-associated MOF inseverely
injured trauma patients.Laterinthecourseoftrauma,
a hypercoagulable state with the occurrence of thromboembolic events
predisposes to MOF. Risk factors for transfusion-associated MOF
include the administration of crystalloids and red blood cells anda
prolonged storage time of red blood cells. However, pooling of data
was hampered by heterogeneity of the study populations and
outcome measures.Future prospective studies investigating TIC-and
transfusion-associated risk factors on late outcome are required.