Such aggregates occurred in cells with the same location and nuclear profile as those showing glycogen storage in diabetic rats; albeit at a much lower level than in the diabetics. As in the diabetic amacrine cells, the glycogen aggregates were typically irregular and located in the perinuclear cytoplasm where they appeared to lie free withi the cytosol and not enclosed by any endomembrane structures (Figs. 1C, 1F insets).