Chauvin et al5 and Drouhet and Dupont7 have had
success using ketoconazole to treat the disease. For
that reason, and due to the duration (six years) and
the relapse after potassium iodide therapy in our
patient's disease, we tried to use ketoconazole. This
drug was used for as long as six months, without side
effects, producing remarkable improvement in the
first two months and cure in six months, without
relapse after three years nine months. Based on some
reports on the recurrent character of this disease,21019
we consider the long-term follow-up of our patient of
capital importance.
Hay15 described C coronatus infection that failed to
respond to a five-month ketoconazole therapy, but in
vitro sensitivity data were not available.
The isolation and identification of the causative
agent is fundamental for the diagnosis of the myco¬
sis. The isolated fungus can also be submitted to
evaluation for in vitro sensitivity to antifungal
drugs, thus allowing a better choice for therapy.