The purpose of present work is to fabricate multifunctional cotton textiles with AgNWs, according to its multiple properties, by a one-step simple “dip and dry” treatment. To this end, AgNWs were synthesized by polyol process and then were dispersed in ethanol to form stable colloidal solution for coating cotton fabric. The treated cotton fabrics were found with high electrical conductivity, excellent UV protective property and antibacterial activity simultaneously. In addition, after coating of a layer of low-surface-energy fluorosilane, superhydrophobicity was obtained. Among the various morphologies of silver nanostructures such as spherical, polygonal, prism and flakes, AgNWs show high one dimensional conductivity due to the unique morphology. Moreover they can be physically attached to the fibers since of their penetrating capability.