Interestingly,we observed a significant inverse correlation between the concentration of vitamin C and concentrations of 8-epi-PGF2 at baseline. Furthermore, after subjects drank the orange juice daily for 14 d, concentrations of 8-epi-PGF2 were reduced by 27%,and the correlation remained the same, even though concentrations of 8-epi-PGF2 and vitamin C changed significantly.