Puberty is a crucial period to achieve the
adequate peak bone mass. Precocious Puberty (PP)
treatment with GnRH agonist inhibits the hypothalamopituiatry-gonadal
hormone secretion and eventually
deprives estrogen. This may affect the acquisition of
peak bone mass. Nutritional intake is one factor influencing
bone mass. People from Western countries
consume a diet containing high calcium such as milk
and cheese. Nevertheless, the reports on the impact of
GnRH agonist on BMD from these countries showed
various results. Such reports from Asian countries
whose people consume less calcium are so limited.
Therefore, the aim of this study was to evaluate the
Bone Mineral Density (BMD), body composition and
bone marker in Thai PP girls treated with GnRH agonist.