On the other hand, and consistent with the screening method by which SUVi has been isolated, a link to RecQ helicases and to their function in UV repair is intriguing.
In E. coli, recovery of replication following UV-induced DNA damage was shown to be dependent upon RecQ.
The function of this helicase affects the sites and frequencies at which illegitimate rearrangements occur following UV-induced damage, suggesting that it also functions during the recovery of replication [12].