Eicosapentaenoic acid (EPA, 20:5n-3) and docosahexae- noic acid (DHA, 22:6n-3) are two major polyunsaturated fatty acids (PUFA), not present in normal skin epidermis. However, they are metabolized by skin epidermal enzymes into anti-inflammatory and anti-proliferative metabolites that are associated with a variety of benefits regarding inflammatory skin disorders [9]. Oil and marine lecithin from salmon (Salmo salar) contains a high percentage of PUFAs, especially EPA and DHA [10,11].