mode has become so far, the most widely used technique
for the quantitation of (polar) pesticides in food as reported
extensively in the literature [3–14]. On the other hand, highresolving
power mass spectrometric techniques such as timeof-
flight mass spectrometry (TOF-MS) have been applied in
the environmental field mainly for structure elucidation or
confirmation purposes [15–19]. LC–TOF-MS has been applied
for confirmatory analyses rather than for quantitation
mainly because of well-known limitations such as the narrow
dynamic range. Another disadvantage has been the lack
of accuracy of some instruments to achieve the 2–5 ppm error
level, usually needed when analyzing complex matrices
for unequivocal identification of the target analytes [19,20].
However, the use of TOF-MS techniques has become necessary
in the last few years for the unequivocal identification
of contaminants and veterinary drugs in meat [21] and to
achieve the EU requirements regarding the number of identification
points for a positive finding [22]. In addition, the use
of TOF-MS allows the capability of non-target identification,
because the full-spectrum is recorded at all times, which is
not possible with standard monitoring practices that use single
ion monitoring or multiple reaction monitoring (MRM)
techniques.
mode has become so far, the most widely used techniquefor the quantitation of (polar) pesticides in food as reportedextensively in the literature [3–14]. On the other hand, highresolvingpower mass spectrometric techniques such as timeof-flight mass spectrometry (TOF-MS) have been applied inthe environmental field mainly for structure elucidation orconfirmation purposes [15–19]. LC–TOF-MS has been appliedfor confirmatory analyses rather than for quantitationmainly because of well-known limitations such as the narrowdynamic range. Another disadvantage has been the lackof accuracy of some instruments to achieve the 2–5 ppm errorlevel, usually needed when analyzing complex matricesfor unequivocal identification of the target analytes [19,20].However, the use of TOF-MS techniques has become necessaryin the last few years for the unequivocal identificationof contaminants and veterinary drugs in meat [21] and toachieve the EU requirements regarding the number of identificationpoints for a positive finding [22]. In addition, the useof TOF-MS allows the capability of non-target identification,because the full-spectrum is recorded at all times, which isnot possible with standard monitoring practices that use singleion monitoring or multiple reaction monitoring (MRM)techniques.
การแปล กรุณารอสักครู่..
mode has become so far, the most widely used technique
for the quantitation of (polar) pesticides in food as reported
extensively in the literature [3–14]. On the other hand, highresolving
power mass spectrometric techniques such as timeof-
flight mass spectrometry (TOF-MS) have been applied in
the environmental field mainly for structure elucidation or
confirmation purposes [15–19]. LC–TOF-MS has been applied
for confirmatory analyses rather than for quantitation
mainly because of well-known limitations such as the narrow
dynamic range. Another disadvantage has been the lack
of accuracy of some instruments to achieve the 2–5 ppm error
level, usually needed when analyzing complex matrices
for unequivocal identification of the target analytes [19,20].
However, the use of TOF-MS techniques has become necessary
in the last few years for the unequivocal identification
of contaminants and veterinary drugs in meat [21] and to
achieve the EU requirements regarding the number of identification
points for a positive finding [22]. In addition, the use
of TOF-MS allows the capability of non-target identification,
because the full-spectrum is recorded at all times, which is
not possible with standard monitoring practices that use single
ion monitoring or multiple reaction monitoring (MRM)
techniques.
การแปล กรุณารอสักครู่..