Several investigations have detailed common barriers to
TTM implementation including lack of knowledge about
methods for cooling and therefore lack of physician
acceptance, perceptions of futility given the presumed poor
prognosis for comatose CA survivors, and insufficient
support from hospital administration [6,8,11]. In addition,
surveyed practitioners have cited process issues such as poor
team coordination and high workload for nursing staff [8,11].
Translating TTM evidence into clinical practice is crucial to
improve survival and quality of life for comatose cardiac
arrest survivors. This concept of moving clinical science
towards broad implementation, known as knowledge
translation, represents a domain of growing interest in
clinical research more generally aimed to help accelerate
evidence into routine practice [12–14]