Preterm birth, defined as birth before gestational
week (GW) 37 + 0, is a central problem in obstetrics
and the single most important risk factor for
perinatal morbidity and mortality (1). In 2011, 9% of all
children born in Germany were born before the end of
GW 37 (2). This rate is high compared to that of most
other European countries (3) (Figure 1); it has
remained stable over the last 10 years, yet the rate of
extremely premature birth, i.e., birth before GW 28, has
risen by 65% (Figure 2). Although the reasons for this
development are not yet fully clear, it is attributed in
large part to known demographic factors such as the
trend toward higher maternal age in pregnancy and the
rising prevalence of diabetes mellitus (4).
Preterm birth, defined as birth before gestationalweek (GW) 37 + 0, is a central problem in obstetricsand the single most important risk factor forperinatal morbidity and mortality (1). In 2011, 9% of allchildren born in Germany were born before the end ofGW 37 (2). This rate is high compared to that of mostother European countries (3) (Figure 1); it hasremained stable over the last 10 years, yet the rate ofextremely premature birth, i.e., birth before GW 28, hasrisen by 65% (Figure 2). Although the reasons for thisdevelopment are not yet fully clear, it is attributed inlarge part to known demographic factors such as thetrend toward higher maternal age in pregnancy and therising prevalence of diabetes mellitus (4).
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