2.7. Pharmacokinetic study
Twelve Beagle dogs were fasted for 12 h before dosing and for
another 4 h post dose, and water was provided ad libitum. In order
to proceed baseline correction, we collected the blank blood samples
using the same schedule as dosing-day in twelve Beagle dogs.
The baseline was investigated the day before dosing-day every
time. Each dog received a single oral dose of 0.25 g/kg BCAAs. Blood