Our final proposed ข้อถือสิทธิS
What is ข้อถือสิทธิed is:
1. A method of measuring a quantity of cancer related substances by Surface
Enhanced Raman Scattering (SERS), the method ซึ่งประกอบรวมด้วย the steps of
preparing a ไบโอชิป having a ผลึกเมโส region of ซิลเวอร์ออกไซด์s containing a
ซิลเวอร์ peroxide, adding dropwise a serum or biological liquid sample to the
ผลึกเมโส region of the ไบโอชิป, selectively trapping cancer related substance
having a positive charge in the sample, irradiating the trapped cancer related
substance with an exciting light, and detecting the surface enhanced Raman
scattering light.
2. The method of ข้อถือสิทธิ 1, โดยที่ the detected Raman scattering spectrum shows
carbon inherent peaks in the zone of D band and G band and a characteristic peak in the vicinity of 2900cm "1 as spectrum of the cancer related substances.
3. The method of ข้อถือสิทธิ 2, โดยที่ the cancer related substance contains a
released DNA (DNA wrapped around the ฮิสโตน: นิวคลีโอโซมs), and the relevant chromatin (chromosome).
4. A ไบโอชิป applicable to the method of measuring the quantity of cancer related
substances according to ข้อถือสิทธิs 1 to 3, which ประกอบรวมด้วย a ผลึกเมโส region of ซิลเวอร์ออกไซด์s containing a ซิลเวอร์ peroxide capable of showing a negative charge in the sample in order to selectively trap cancer related substances having a
positive charge in the sample and also showing surface enhance resonance
phenomenon by irradiation of an exciting light such as laser thereon.