] The nutritional composition may also contain TGF-β. In some
รุรุ, the level of TGF-β may be from about 0.0150 (pg/µg) ppm to about
0.1000 (pg/µg) ppm. In other รุรุ, the level of TGF-β in final composition ที่รวมถึง a stabilized probiotic is from about 0.0225 (pg/µg) ppm to about 0.0750 (pg/µg) ppm.
[0109] In some รุรุ of the nutritional composition, the level of TGF-β is
from about 2500 pg/ml to about 10,000 pg/ml, more preferably from about 3000 pg/ml to about 8000 pg/ml. ในรุรุหนึ่ง, the ratio of TGF-β 1: TGF-13i2 is in the range of about 1 :1 to about 1 :20, or, more particularly, in the range of about 1 :5 to about 1 :15. [0110] In some รุรุ, the bioactivity of TGF-β in a nutritional composition
is enhanced by the addition of a bioactive whey fraction. Any bioactive whey fraction
known in the art may be used in such รุรุ provided it achieves the intended result. ในรุรุหนึ่ง, this bioactive whey fraction may be a whey protein concentrate. In a particular embodiment, the whey protein concentrate may be Salibra®
800, available from Glanbia Nutritionals.
[0111] The nutritional composition may ประกอบรวมด้วย an amount of probiotic in addition to the stabilized probiotic. When the stabilized probiotic is combined with the
nutritional product, the resulting nutritional composition may include a total amount of probiotics effective to provide from about 1 x 104 to about 1 x 1010 colony forming units (cfu) per kg body weight per day to a subject. In other รุรุ, the amount of the pro biotic may vary from about 1 x 106 to about 1 x 109 cfu per kg body weight per day.
In even further รุรุ, the nutritional composition may include an amount of probiotics effective to provide about 1 x 106 cfu per kg body weight per day.
[0112] In certain รุรุ, the nutritional composition of the present
disclosure ประกอบรวมด้วย ระหว่างประมาณ 1 x 106 cfu pro biotic ถึงประมาณ 1 x 1010 cfu per 100 kcal of the composition. In some รุรุ, the amount of probiotic may be in the range of about 1 x 106 cfu to about 1 x 109 cfu per 100 kcal of the composition. Additionally, the nutritional composition may include non-stabilized probiotics, with the final composition ที่รวมถึง some stabilized probiotics and some non-stabilized
probiotics.
[0113] The nutritional composition may further ประกอบรวมด้วย at least one prebiotic.