A short interpregnancy interval is associated with
IUGR [42]. Artificial reproductive techniques (ART) and
infertility are independent risk factors of IUGR. There is
some evidence that superovulation can affect DNA methylation,
causing imprinting changes, which can affect fetal
growth and development. Singleton infants resulting from
in vitro fertilization (IVF) and superovulation without
ART are at higher risk for LBW and SGA compared with
no treatment; however, no such association is found in
multiple pregnancies