Identification of all herbal medicines was verified by Professor Bae of the College of Pharmacy, Chungnam National University, and the specimens of these
herbs were deposited at Korean Institute of Oriental Medicine (KIOM). Each herbal medicine was extracted by heating in water of 8 to 10 times of the herb weight for 3 hours at 115 ◦C (Gyeongseo Extractor Cosmos-600, Incheon, Korea).