Other drugs may be included in the therapy plan, depending on the hemorrhage. Corticosteroids are given for hematuria, acute hemarthrosis, and chronic synovitis. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are effective in relieving pain caused by synovitis; however, they must be used with caution because they inhibit platelet function (Curry, 2004; National Hemophilia Foundation, 2006). Oral administration of €-aminocaproic acid (Amicar) prevents clot destruction; however, its use is limited to mouth or trauma surgery, and a dose of factor concentrate must be given first.