it is seen in Fig. 7 that the capacity to bind anti-ds-DNA IgG is leveling off for the filter paper in the region between 2.5 and 5.0 mg DNA/g cellulose, while
it progressively increases for the nanocellulose sample. Thus, it
appears that distribution of DNA on the surface of cellulose is an
important factor controlling the interactions between ligand and
target antibody.
The results of the present work suggest that DNA coating is
most likely limited to the outer surface of the membrane. The latter indicates that it will be more efficient to reduce the thickness
of the membrane to increase the weight specific capacity of the
membrane and minimize non-specific binding.