Liver synthesizes cholesterol. It is then packaged and distributed to the body or excreted into bile for removal from the body.
Increased cholesterol concentrations in bile may predispose to gallstone formation. The liver also synthesizes lipoproteins. These are made up of cholesterol, triglycerides phospholipids, and proteins.
Lipoproteins transfers cholesterol between the liver and body tissues. Most liver diseases do not significantly affect serum lipid levels. However, cholestatic diseases, may be associated with increased levels.