Thevehicle was hypromellose ointment ((20 g hypromellose (hydroxypropylmethyl cellulose), 400 mPa s in 80 g white soft paraffin, according to the Dutch formulary Formularium der Nederlandse Apothekers(FNA) (Hypromellosezalf 20%, 2013) and obtained from Fagron,Capelle aan den IJssel, the Netherlands)).