The presence of DSM-IV or -5 psychopathology might be causally related with the perpetrated crime beyond the presence of aggressive impulsiveness-related genes, hence it is on clinical grounds that the possible sentence reduction should be considered, independently from the presence or absence of culprit genes. The presence of these genes, should the results pointing to their involvement in criminal acts be obtained, might increase the odds for the crime to occur, but their pathophysiological link with the crime should be demonstrated before asking for sentence reduction in cases where the convict’s DNA analysis yields positive results.