This paper presents development and validation of three analytical models for flexure-dominated Interlocking Compressed Earth Block (ICEB) walls, which are based on classic mechanics of materials, inelastic truss elements, and phenomenological hysteretic model, respectively. Based on the testing results from a prior experimental investigation, it is shown that the first two models provide reasonable estimates for the lateral load resistance of flexure-dominated ICEB walls and the third model captures the inelastic behavior of flexure-dominated ICEB walls under cyclic loading. Using the third model, incremental dynamic analyses were conducted and performances of two demonstration single-story buildings consisting of flexure-dominated ICEB walls were evaluated for three construction sites with different levels of seismicity. Computer simulation results show that both demonstration buildings are able to avoid earthquake-induced collapse. It is also found that the current design and construction of flexure-dominated ICEB walls may be overly conservative for a site with relatively low seismicity.