The second objective of this study was to determine whether a balance training program was equally effective in reducing the rate of ankle sprains in subjects with and without a history of an ankle sprain. None of the prior studies has been able to document that a proprioceptive training program will significantly reduce the incidence of ankle sprains in athletes without a prior sprain. Our results suggest that a balance training program will reduce the rate of ankle sprains in athletes who have not had a prior ankle sprain. However, our results approached (P < .059) but did not attain statistical significance.This finding was attributed in large part to the fact that there were fewer sprains (n = 62) than the number we projected (n = 87) based on the incidence of acute sprains reported in other studies.